Oral Biopsy

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Oral Biopsy
What is an oral biopsy?
  • An oral biopsy is a procedure where a sample(s) of the tissues in your oral cavity is removed surgically and then transported to a laboratory to have the cells in the tissue reviewed under a microscope.
  • An oral pathologist reviews the cells under the microscope and describes their findings (which also usually includes a diagnosis) in a report, which is sent back to the clinician who undertook the oral biopsy procedure.
What are the types of oral biopsies?
MOSS offers two common types of oral biopsies – excisional and incisional. These types of biopsies can be applied to either the oral soft tissues or the oral hard tissues (jaw bones including mandible and maxilla)
Type of biopsy Excisional Incisional
Description Entire lesion removed Part of lesion removed
Clinical suspicion Benign Suspected malignancy or unknown diagnosis
Size Usually, < 1cm Usually, >1cm
What are the potential benefits of an oral biopsy?
  • Diagnostic – e.g confirm or exclude a diagnosis
  • Therapeutic – e.g remove an irritating lesion
  • Provide additional reassurance: e.g there are ‘no cancer cells’ in this lesion
What am I likely to experience during the procedure?

The procedure is quick to perform and the combination of happy gas sedation and local anesthesia ensures that you remain relaxed and comfortable throughout.

  • Local anaesthetic – an injection to get you numb
  • Removal lesion (whole/partial) usually with a scalpel or similar instrument
  • Suturing of the soft tissues together to promote healing where applicable
  • Placement of gauze over the biopsy site to help control any bleeding
What am I likely to experience during the post operative recovery?

The oral biopsy procedure is usually fairly minor and you are likely to make a full recovery in a couple of days. You would not usually need time off work to recover. You may experience

  • Minor soreness
  • Minor swelling
  • Slow bleeding, which may occur intermittently for the next couple of days but is easily controlled by firmly pressing gauze for 30 minutes.
What are the potential risks and/or side effects?
  • A complication from an oral biopsy procedure is a rare occurrence.
  • The majority of patients make a full recovery after the biopsy procedure.
  • Potential risks of the procedure include the following:
Category of risk Discussion points
Common Scar, numbness, bleeding, soreness – often unnoticeable, minor or self-resolving
Rare Lesion recurrence
Indeterminate histopathology result
Potential need for additional investigation, referral +/- hospital management
If patient specific risk factors are present (e.g smoking, immunocompromised) Infection
Non-healing biopsy site
Anatomical specific risk factors Injury to adjacent vital structures such as nerve, artery, duct or sinus (if applicable)
Do I need to see a specialist?

Lesions in the oral cavity can be very complex and may be due to a medical condition elsewhere in the body.
Dr Daniel will assess you clinically including a history, examination, radiographic examination and histopathological examination, where applicable. Depending on the diagnosis, you may require

  1. no further management or monitoring
  2.  further management and monitoring
  3. referral for specialist management which may or may not be required in the hospital setting. Common specialists that manage oral & related conditions include Oral Medicine Specialist, Oral and Maxillofacial Surgeon, Ears, Nose and Throat Surgeon, a Dermatologist or a Rheumatologist.
Do I need antibiotics for this procedure?
  • Healthy patients undertaking a simple oral biopsy procedure do not require antibiotics.
  • Some patients with certain high risk heart conditions require a single dose of an oral antibiotic 1hour before the procedure.
  • Some patients who are severely immunocompromised may require a short course of oral antibiotics after the procedure.
Post operative instructions:
Feature Do Don’ts 
Rest

Return to work same day

Usual activities of daily living

Strenuous activity for 3 days
Nutrition

Aim to drink over 1-1.5L of water / day

Regular diet

Hot and cold foods for 6hours after the procedure

Hard or sharp foods such as nuts & chips for the first 2 weeks

Alcohol for 2 weeks

Oral hygiene

Brush teeth twice a day

Gently rinse 10mLs of Curasept Mouthrinse (antibacterial) in your mouth for 30 seconds then spit out, four times a day, until the bottle is finished.

Brushing the biopsy site

Food remaining stuck at biopsy site (rinse it off)

Smoking (1month)

Pain

May be sore for a couple of days

Take two 500mg paracetamol tablets four times a day for 2 days then as required

Take one 200mg neurofen tablet three times a day as required

Take neurofen for more than 5 days
Swelling Usually there will be a minimal amount of swelling from the biopsy site which may increase for 2 days before resolving by the end of the week N/A
Bleeding

The biopsy site might bleed slowly on and off for a couple of days after the procedure

Place gauze over the biopsy site and apply firm pressure for 30minutes. If bleeding re-occurs, repeat this step.

Don’t check the bleeding every 5minutes once you have placed the gauze there (it usually takes 30minutes for the bleeding to settle with firm pressure)
Do I need a follow up appointment after this procedure?
  • An appointment will be scheduled to review you by tele consult approximately 2 weeks after the procedure & to inform you of the histopathology result & additional management or referrals if required.
Who will be undertaking the oral biopsy procedure?
  • Dr Daniel, a currently registered and practicing Dentist with the Australian Health Practitioner Regulation Agency (AHPRA) will be undertaking the oral biopsy procedure.
  • He has also completed a medical degree and has worked in the hospital system as a medical practitioner for over half a decade.
  • Dr Daniel has undertaken a year of surgical training in the hospital system in the Oral and Maxillofacial Surgery department at a registrar level where he routinely managed oral pathology and performed oral biopsy specimens under the auspices of the Oral and Maxillofacial Surgeons.
  • He currently undertakes oral biopsy procedures in private practice regularly with excellent results.
How much is the oral biopsy going to cost me?
  • The prices depends on the type and complexity offered and a formal quote will be provided at the consultation appointment. Consultation appointments are held by teleconsult for 20 min and has a fee of $90.